DRUGS FOR NOT INHALATION NARCOSIS
Most often general anesthetize substances appoint animal inhalation (hypodermically, intramuscularly, but intravenously). These ways are convenient that give an opportunity to create for long time a desirable degree narcosis for, is fast narcosis animals, not resorting to their complex fixation; valuable in most cases is also long after a narcotic dream. Besides at not inhalation narcosis (except for oral introduction) the stage of anxiety happens short-term and poorly expressed. Danger of overdose goes down, if first half of doze enter quickly, and the second - slowly and at the exact control as depths of a narcosis, and a condition of an animal.
It is a lot of not inhalation drugs and at intravenous introduction of the most distinctive duration of action is. For example, propandiol--3-10 mines, tiopental and hexachenal--20-45 mines, sodium oxibuterat--100-120 minutes the Greatest value present preparations birbiture acids, chlorine ethane and alcohol; alcohol render versatile influence on an organism.
Itself bromic achide does not render drugs or somnifacient action. But at replacement in it of hydrogen atoms near carbon in 5 and 51 position alkyl, aryl and any other radicals connections, many of which are rather active drugs turn out.
The Bromik derivatives received at replacement hidrogen in 5 position, are very badly dissolved in water and consequently are suitable mainly as is long acting sleeping medicines at oral application. Introduction of sodium in the second location raises solubility of connections and allows to apply them parenteral.
From a plenty of preparations barbiturate acids had extrem used in veterinary practice have received greater distribution tiopental and hexenal; are much less often used barbital, hexobarbital, phenobarbital and, partly, barbital-sodium.